Van Til discusses the foundational difference between biblical faith and unbelieving philosophy as expressed in Roman Catholicism, Joseph Butler, Aquinas, and Aristotle. The Creator-creature distinction, he argues, requires humans to submit to the incomprehensibility of God in their thinking.

Van Til discusses the point of contact, autonomy, the antithesis between belief and unbelief, the roles of faith and reason, and the theistic proofs.

Van Til contrasts New Protestantism with biblical Christianity, showing the assumptions of modern theology, and critiquing probabilistic apologetics and theology.

Van Til compares Calvin's understanding of God, sin, and grace to Roman Catholicism and Aristotle. He also explores common grace according to Scripture and the honest offer of the gospel.

Van Til makes a passionate plea for Calvinism in America to start engaging more with culture and the public square, in the spirit of Abraham Kuyper.

Van Til begins a discussion of Thomas Aquinas and his importance to Roman Catholic thought. He also shows how Reformed thought and apologetics differs fundamentally in terms of its starting point.

Van Til lectures on the genius of St. Augustine and how he continued to struggle with platonic influence, even though his biblical faith was sincere and won out over Platonism.

Van Til calls on Christians to wage war against Satan in the realm of culture by reclaiming Christian education for Christ.